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Identification of Iodotyrosines as Novel Substrates for the Thyroid Hormone Transporter MCT8
(2024)ThyroidBackground: Monocarboxylate transporter 8 (MCT8) is the most specific thyroid hormone transporter identified to date, deficiency of which has been associated with severe intellectual and motor disability and abnormal serum thyroid function tests. However, it is presently unknown if MCT8, similar to other thyroid hormone transporters, also accepts additional substrates, and if disruption of their transport may contribute to the observed ...Journal Article -
The influence of uncertainty visualization on cognitive load in a safety- and time-critical decision-making task
(2024)INTERNATIONAL JOURNAL OF GEOGRAPHICAL INFORMATION SCIENCEDecisions with spatial visualizations are often made under uncertainty and high time pressure. However, missing or improper representation of uncertainty can hamper the decision-making process. This paper investigates the impact of uncertainty visualization on cognitive load in the context of a safety-critical, time-sensitive decision-making task with a transportation system map. In a controlled experiment (n = 40) with a dual-task paradigm, ...Journal Article -
Seminatural areas act as reservoirs of genetic diversity for crop pollinators and natural enemies across Europe
(2024)CONSERVATION SCIENCE AND PRACTICEDespite increasing recognition of the importance of the multiple dimensions of biodiversity, including functional or genetic diversity as well as species diversity, most conservation studies on ecosystem service-providing insects focus on simple diversity measures such as species richness and abundance. In contrast, relatively little is known about the genetic diversity and resilience of pollinators or natural enemies of crop pests to ...Journal Article -
Time-Resolved Oxidation State Changes Are Key to Elucidating the Bifunctionality of Perovskite Catalysts for Oxygen Evolution and Reduction
(2024)ENERGY & ENVIRONMENTAL MATERIALSIn a unified regenerative fuel cell (URFC) or reversible fuel cell, the oxygen bifunctional catalyst must switch reversibly between the oxygen reduction reaction (ORR), fuel cell mode, and the oxygen evolution reaction (OER), electrolyzer mode. However, it is often unclear what effect alternating between ORR and OER has on the electrochemical behavior and physiochemical properties of the catalyst. Herein, operando X-ray absorption ...Journal Article -
Frequency Matters: Comparative Analysis of Low-Power FMCW Radars for Vital Sign Monitoring
(2024)IEEE Transactions on Instrumentation and MeasurementVital sign monitoring is a critical step in health assessment in clinical settings. A rising interest in contactless options is pushing for innovative solutions for heart rate (HR) and respiration rate (RR) estimation. Low-power millimeter-wave radars are emerging as a solution because of their invariance to lightning conditions, subject phenotype, and privacy guarantees. On the side, the robustness of radar-based systems is still a concern ...Journal Article -
Single-Step Control of Liquid-Liquid Crystalline Phase Separation by Depletion Gradients
(2024)ADVANCED MATERIALSFine-tuning nucleation and growth of colloidal liquid crystalline (LC) droplets, also known as tactoids, is highly desirable in both fundamental science and technological applications. However, the tactoid structure results from the trade-off between thermodynamics and nonequilibrium kinetics effects, and controlling liquid-liquid crystalline phase separation (LLCPS) in these systems is still a work in progress. Here, a single-step strategy ...Journal Article -
<i>In Situ</i> Formation of Platinum-Carbon Catalysts in Propane Dehydrogenation
(2024)Angewandte Chemie. International EditionThe catalytic production of propylene via propane dehydrogenation (PDH) is a key reaction in the chemical industry. By combining operando transmission electron microscopy with density functional theory analysis, we show that the intercalation and ordering of carbon on Pt interstitials to form Pt-C solid solutions is relevant for increasing propylene production. More specifically, we found that at the point of enhanced propylene formation, ...Journal Article -
Perspectives on ultra-processed foods as vehicles for food fortification
(2024)Trends in Food Science & TechnologyBackground: The rising popularity in low- and middle-income countries (LMICs) of ultra-processed foods (UPFs), defined by the Nova classification system, makes them an appealing option for food fortification initiatives to address micronutrient deficiencies in vulnerable populations. However, significant controversy surrounds this issue given that higher intake of UPFs is associated with a range of health risks including development of ...Journal Article -
Wavelet-Based Density Estimation for Persistent Homology
(2024)SIAM/ASA Journal on Uncertainty QuantificationPersistent homology is a central methodology in topological data analysis that has been successfully implemented in many fields and is becoming increasingly popular and relevant. The output of persistent homology is a persistence diagram ---a multiset of points supported on the upper halfplane ---that is often used as a statistical summary of the topological features of data. In this paper, we study the random nature of persistent homology ...Journal Article -
Was H 2 O 2 generated before oxygenic photosynthesis?
(2024)Redox BiologyWe obviously agree with Wu et al. that H2O2 might accumulate in the Archean land waters devoid of Fe2+. We do disagree on the topic of the half-life of H2O2, as the work cited in support for a longer half-live is not relevant to the conditions in the Archean ocean. While the existence of radicals in quartz is not in doubt, we do question the hypothesis that these radicals oxidize water to HO center dot and H2O2.Journal Article -
Effects of impurities on the ice microstructure of Monte Perdido Glacier, Central Pyrenees, NE Spain
(2023)Annals of GlaciologyMonte Perdido Glacier, located in the central Pyrenees, is one of the southernmost glaciers in Europe. Due to climate change, this glacier is suffering an accelerated mass loss, especially in the last decades. If the current trends persist, this glacier is expected to disappear in the next 50 years. As part of the efforts of the scientific community to increase the knowledge about this glacier, this research presents the first microstructural ...Journal Article -
S<sup>3</sup>M-Net: Joint Learning of Semantic Segmentation and Stereo Matching for Autonomous Driving
(2024)IEEE Transactions on Intelligent VehiclesSemantic segmentation and stereo matching are two essential components of 3D environmental perception systems for autonomous driving. Nevertheless, conventional approaches often address these two problems independently, employing separate models for each task. This approach poses practical limitations in real-world scenarios, particularly when computational resources are scarce or real-time performance is imperative. Hence, in this article, ...Journal Article -
The SPHERE view of the Taurus star-forming region: The full census of planet-forming disks with GTO and DESTINYS programs
(2024)Astronomy & AstrophysicsThe sample of planet-forming disks observed by high-contrast imaging campaigns over the last decade is mature enough to enable the demographical analysis of individual star-forming regions. We present the full census of Taurus sources with VLT/SPHERE polarimetric images available. The whole sample sums up to 43 targets (of which 31 have not been previously published) corresponding to one-fifth of the Class II population in Taurus and about ...Journal Article -
The SPHERE view of the Chamaeleon I star-forming region: The full census of planet-forming disks with GTO and DESTINYS programs
(2024)Astronomy & AstrophysicsContext. The past few years have seen a revolution in the study of circumstellar disks. New instrumentation in the near-infrared and (sub)millimeter regimes have allowed us to routinely spatially resolve disks around young stars of nearby star-forming regions. As a result, we have found that substructures with scales of ~10 au in disks are common. We have also revealed a zoo of different morphologies, sizes, and luminosities that is as ...Journal Article -
On Solute Recovery and Productivity in Chiral Resolution through Solid-State Deracemization by Temperature Cycling
(2024)Crystal Growth & DesignTemperature cycling represents an effective means for the deracemization of chiral compounds that crystallize as conglomerates and racemize in solution. In such a process, a suspension enriched in the desired enantiomer is converted into an enantiopure one through periodic cycles of crystal dissolution and crystal growth. We show that performing temperature cycling at higher temperatures leads to faster deracemization and, consequently, ...Journal Article -
Directly imaging spin polarons in a kinetically frustrated Hubbard system
(2024)NatureThe emergence of quasiparticles in quantum many-body systems underlies the rich phenomenology in many strongly interacting materials. In the context of doped Mott insulators, magnetic polarons are quasiparticles that usually arise from an interplay between the kinetic energy of doped charge carriers and superexchange spin interactions1-8. However, in kinetically frustrated lattices, itinerant spin polarons-bound states of a dopant and a ...Journal Article -
Flexural pulse wave velocity in blood vessels
(2024)The Journal of the Acoustical Society of AmericaArteriosclerosis is a major risk factor for cardiovascular disease and results in arterial vessel stiffening. Velocity estimation of the pulse wave sent by the heart and propagating into the arteries is a widely accepted biomarker. This symmetrical pulse wave propagates at a speed which is related to the Young's modulus through the Moens Korteweg (MK) equation. Recently, an antisymmetric flexural wave has been observed in vivo. Unlike the ...Journal Article -
Electric Fields Are a Key Determinant of Carbapenemase Activity in Class A β-Lactamases
(2024)ACS CatalysisResistance to antibiotics is a public health crisis. Although carbapenems are less susceptible to resistance than other β-lactam antibiotics, β-lactamases mediating resistance against these drugs are spreading. Here, we dissect the contributions of electric fields to carbapenemase activity in class A β-lactamases. We perform QM/MM molecular dynamics simulations of meropenem acyl-enzyme hydrolysis that correctly discriminate carbapenemases. ...Journal Article -
Observation of Nagaoka polarons in a Fermi-Hubbard quantum simulator
(2024)NatureQuantum interference can deeply alter the nature of many-body phases of matter1. In the case of the Hubbard model, Nagaoka proved that introducing a single itinerant charge can transform a paramagnetic insulator into a ferromagnet through path interference2-4. However, a microscopic observation of this kinetic magnetism induced by individually imaged dopants has been so far elusive. Here we demonstrate the emergence of Nagaoka polarons ...Journal Article -
Bridging cognitive neuroscience and education: Insights from EEG recording during mathematical proof evaluation
(2024)Trends in Neuroscience and EducationBackground: Much of modern mathematics education prioritizes symbolic formalism even at the expense of non-symbolic intuition, we contextualize our study in the ongoing debates on the balance between symbolic and non-symbolic reasoning. We explore the dissociation of oscillatory dynamics between algebraic (symbolic) and geometric (non-symbolic) processing in advanced mathematical reasoning during a naturalistic design. Method: Employing ...Journal Article